There has been much debate about why Covid-19 outbreaks in some parts of the world quickly overwhelmed health systems, while at other locations the outbreak could be readily managed.
“Was it something about those communities and their response, or had the virus somehow changed?”
The study explained how all viruses mutate and change to some degree but those changes “rarely impact fitness or ability to compete”.
The significant change with respect to SARS-CoV-2 variant was the presence of D614G mutation which was absent in the earliest regional outbreaks.
The experts, however, have called for more research, concluding that the Covid-19 virus may have ultimately figured out how to be more stable and not fall apart.
“Over time, it has figured out how to hold on better and not fall apart until it needs to,” co-author Michael Farzan, PhD, co-chairman of the Scripps Research Department of Immunology and Microbiology said. “The virus has, under selection pressure, made itself more stable,” he added.